MC4R Pharmacochaperone as a Novel Therapeutic Strategy for Genetic Forms of Early-Onset Obesity
Time: 11:30 am
day: Conference Day One
Details:
- MC4R mutations resulting in receptor trafficking default as the cause of early onset obesity
- Therapeutic use of small molecule pharmacochaperones to rescue plasma membrane trafficking of MC4R
- Presentation of an unique toolbox made of in vitro and genetic in vivo models, and of in vivo proof-of-concept data
