Uwe Grether

Company: Roche

Job title: Expert Scientist

Seminars:

Panel discussion: Decipher the Biology & Achieve Therapeutic Potential of Human GPCRs from Discovery to Clinical Development 2:00 pm

How to overcome translational challenges such as animal model selection, off target effects, biomarker identification and patient selection to develop a robust pipeline of safe, effective and disease relevant GPCRs targeting drugs • How can previous clinical data of GPCRs candidate relate to new findings and novel strategies How do we efficiently identify, and successfully…Read more

day: Conference Day Two

Integrating Medicinal Chemistry & Chemical Biology for a Translational GPCR Drug Discovery Strategy 3:00 pm

Labelled chemical probes are instrumental in target localization, mechanistic studies, assay development, and establishing biomarkers for target engagement. Integrating medicinal chemistry with chemical biology in a comprehensive, translational end-to-end drug discovery strategy can expedite the development of novel GPCR therapeutics. Productive partnerships between industry and academia can significantly accelerate drug discovery activities.Read more

day: Conference Day Two