Unleashing GPCR Drug Discovery: From Static Structures to Dynamic Insights

• Harnessing cryo-EM and X-ray crystallography to reveal receptor structures and guide simulation-ready models
• Animating GPCRs through molecular dynamics in lipid bilayers to decode ligand binding, activation, and biased signalling
• Accelerating drug discovery via structure-based virtual screening to identify novel therapeutics and mutation-specific strategies

Speakers:

Irina Tikhonova

Molecular Modelling Reader

Queen's University Belfast