Roundtable Discussion: How Can We Advance GPCR Drug Discovery Through Cell-Based Screening & Structural Biology?
- How can we best balance studying GPCRs in their native cellular environment versus using isolated or recombinant proteins?
- Which protein sourcing and experimental system approaches optimise GPCR stability, activity, and translational relevance?
- What structural biology strategies, including cryo-EM and NMR, are most effective for guiding rational GPCR drug design?