Accelerating Therapeutic Success by Connecting GPCR Targets to Actionable Biology: Allosteric Regulators of Free Fatty Acid Receptor 2

• Structural insights into multiple binding pockets for allosteric regulators of FFA2
• Defining the molecular basis for PAM versus NAM activity of ligands that bind to overlapping sites
• Assessment of tissue-selective function of such modulators

Speakers:

Graeme Milligan

Professor of Biochemistry

University of Glasgow